Drug name: Tenox
- amlodipine maleate
Therapeutic effects of Tenox: Tenox contains amlodipine maleate as its active ingredient. The said component belongs to a group of medicines called calcium channels blockers. Amlodipine produces antianginal and hypotensive effects that are caused by the blockage of calcium channels. This results in a decreased amount of transmembrane entrance by calcium ions into the cells.
Antianginal action is linked to the dilating of coronary and peripheral arteries as well as that of the arteriols. Amlodipine eases the symptoms of angina by extending peripheral arteriols, lessening peripheral resistance, lowering cardiac preload as well as the oxygen requirement of heart tissue.
The hypotensive effect of Amlodipine is highly dependent on its dosage. The said action is associated with a direct vasodilating influence on the smooth muscles of the vessels. This decreases the myocardial hypertrophy of the left ventricle as well as the exertion of anti-atherosclerotic effect. It also produces cardioprotective action in coronary heart disease. Amdlodipine does not act upon the contractility and conductibility of the myocardium. Also, it does not bring about the reflective surge in heart rate.
Indications: Tenox is administered to treat cardiovascular disorders such as:
- Coronary artery spasm (Prinzmetal's angina)
- Chest pain due to ischemia (Angina pectoris)
Precautions and Restrictions: Avoid using Tenox under the following circumstances:
- If you are increasingly sensitive to dihydropiridine or amlodipine
- Occlusion (Arterial stenosis)
- Damaged heart that it is unable to supply enough blood to the organs of the body (Cardiogenic shock)
- Condition in which the heart muscle becomes thick (Hypertrophic cardiomyopathy)
- Rapid heartbeat rate (Tachycardia)
- Depression of arterial pressure (Arterial hypotension)
- Vasculogenic shock
- In the first month after heart attack (Myocardial infarction)
- If the user is below the age of 18
- If you are pregnant
- If you are a nursing mother
Use this drug with caution before, during, or after pregnancy and discuss about this with your doctor.
Observe caution while using Tenox if:
- You suffer from liver damage
- You suffer from hear rhythm disorder such as Sick sinus syndrome
- You suffer from heart failure
- You have diabetes
- You suffer from lipid metabolism disorders
- You are an elderly person
- Users are advised to control their body weight and maintain dental hygiene while using this medicine.
- Once if you have started using Tenox you have to persist with it till the prescribed treatment period is over. Do not discontinue this medicine in the middle even if you feel better.
- Grapefruit juice may decrease the levels of amdodipine maleate in blood.
Side effects of Tenox: The use of Tenox tablets may cause some side effects, but it is not certain that these side effects will affect every user of this drug. Some of the most common side effects of Tenox include abnormal heartbeat, migraine, swelling and fluid retention, dizziness, flushing, and exhaustion.
Few of the lesser common side effects that users may experience are the urge to vomit, stomach ache, and sleepiness.
The above mentioned side effects are by no means exhaustive, so for the complete list of adverse reactions and possible side effects please see the information provided by the drug manufacturer or consult a doctor or a pharmacist.
Interactions: It is advisable to consult a doctor before taking Tenox tablets. Apprise him of the treatment or medication you are currently under and also get a prescription from your doctor before starting any new drug. This is to make sure that the combination of the two drugs is safe. Tell your doctor if you are using the below mentioned medicines:
- Antipsychotic drugs
- Alcoholic beverages
- Narcotic substances, anesthetics
- Allopurnol, cytostatics, immunologic depressants, glucocorticoids, procainamide
- Lithium preparations
- Non-steroidal anti-inflammatory drugs
- Diuretic drugs that do not promote the secretion of potassium into the urine such as Spironolactone
- Other hypertensive medicines: Water pills, ACE inhibitors, B-blockers, calcium channel blockers and others.
Additional Information: Medicines should not be used without prior approval of a qualified medical care provider and don't share these drugs with anybody else. Tenox tablets are made for specific conditions and it's not advisable to use them for other purposes. Keep medicinal drugs out of the reach of children.