Drug name: Exforge

Active Ingredients:

• Amlodipine and Valsartan

Therapeutic effect of Exforge: Exforge is a medicine used to treat high blood pressure. This drug contains two main ingredients that work together to reduce high blood pressure. The two ingredients amlodipine and valsartan have proven to be very effective in acting against hypertension. Amlodipine is a potent calcium channel blocker that relaxes the muscle of the arterial wall and reduces the resistance thereby decreasing the blood pressure. On the other hand Valsartan is an angiotensin II receptor antagoist (angiotensin receptor blocker or ARB) that acts by blocking angiotensin, a compound that narrows the blood vessels. Valsartan through its blocking action dilates blood vessels and decreases the blood pressure.

Indications: Exforge is primarily used for treating hypertension.

Precautions and Restrictions: Avoid taking Exforge if the following applies to you:

• High sensitivity to any of the ingredients used in Exforge
• Pregnancy
• Lactation

Before taking Exforge talk to your doctor if you have the following conditions:

• Hypovolemia
• Hyperkalemia
• Various cardio vascular disorders like cardiomyopathy, heart attack, stroke, congestive heart failure etc.
• Serious kidney disorders
• Serious liver disorders

Side effects of Exforge: The use of this medicinal drug may give rise to some side effects that are contrary to what is expected. It is not certain that these adverse reactions will affect every user of this drug.

Some of the common side effects are dizziness, upper respiratory tract infection, rhinorrhea, throat pain and water retention.

Some of the serious side effects of Exforge are Hyperkalemia, high blood sugar levels, weight gain, angst, depression, signs of hypotension and arrhythmias.

The above mentioned list of side effects is by no means exhaustive, so for the complete list of adverse reactions and possible side effects please see the information provided by the drug manufacturer or consult a doctor or a pharmacist.

Interactions: There is a high probability of Exforge reacting with other medicines. Exforge may also react with other medicines or substance you are currently using, so before taking this drug it's best to check with your physician or pharmacist or any medical expert. This is to make sure that the combination of the two drugs is safe.

Some of the drugs or substances that react with Exforge are:

• Aldosterone antagonists
• Drugs that promote the formation of urine such as triamterene
• Potassium preparations
• NSAIDs (non-steroidal anti-inflammatory drugs)
• Drugs used in the treatment of congestive heart failure and cardiac arrhythmia (Cardiac glycosides)
• Alcohol
• And other medicines used for treating high blood pressure such as Beta blockers, Angiotensin II receptor blockers, Calcium channels blockers and Calcium channels blockers

Additional Information: These blood pressure controlling medicines should not be used without prior approval of a trained physician and don't share these drugs with anybody else. Exforge tablets are made for specific conditions and it's not advisable to use them for other purposes. Keep medicinal drugs out of the reach of children.