Drug name: Trichopol

Other names used:

• Flagyl®

Active Ingredients:

• Metronidazole

Therapeutic effects of Trichopol: Trichopol is an anti protozoa agent with antibacterial capabilities. Action mechanism is linked to the biochemical reduction of metranidaziole 5-nitrogroup through the intracellular transport proteins of anaerobic microorganisms and protozoa. The 5-nitrogroup interacts with the microorganisms' DNA cells; this disrupts the synthesis of nucleic acids. This interruption is fatal to the microorganisms.

Trichopol can be effectively used against Trichomonas vaginalis, Gardnerella vaginalis, Giardia intestinalis, Entamoeba histolytica. This reliable effect also holds true for anaerobic bacteria Bacteroides spp. like Bacteroides fragilis, Bacteroides distasonis, Bacteroides ovatus, Bacteroides thetaiotaomicron, Bacteroides vulgatus, as well as Fusobacterium spp. and Veillonela spp.

A number of gram-positive bacteria can also be affected by Trichopol, this includes Eubacterium spp., Clostridium spp., Peptococcus spp., and Peptostreptococcus spp.

Indications: Trichopol is used to treat:

• Sexually transmitted infection caused by the parasite Trichomonas vaginalis (Trichomoniasis)
• Intestinal infection caused by the parasite giardia lamblia (Giardiasis)
• Collection of pus in the liver in response to an intestinal parasite caused by amebiasis (Amebic liver abscess)
• Anaerobic bacteria infections
• Preventing problems of the intestine after surgery such as appendectomy, gynecological interventions

Precautions and Restrictions: Avoid using Trichopol under the following circumstances:

• If you are pregnant
• If you are a nursing mother
• If you are allergic or increasingly sensitive to the ingredients of this medicine

In case you have any of the below mentioned conditions you should first talk to a doctor before taking this medicine:

• If you suffer from seizures
• If you suffer from serious liver or renal ailments
• If you are an alcoholic
• If you suffer from epilepsy

Side effects of Trichopol: Use of Trichopol tablets or vaginal tablets may cause certain side effects. The below mentioned side effects may not occur to every user of this medicine. Some of the common side effects include symptoms resembling flu, infections caused by bacteria, metallic taste, urge to vomit, irritation in vagina, cephalalgia, etc.

Few of the lesser occurring side effects include infection of the urinary tract, dry mouth, infection of the vagina, most commonly due to the fungus Candida albicans, pain during menstrual cycle, sore throat, infections of the sinuses, runny nose, infections of the upper respiratory tract, diarrhea, impairment in spatial perception and stability (dizziness), and genital itching. The above mentioned lists of side effects is not comprehensive hence for a detailed list kindly consult a doctor or see the information provided by the manufacturer of this medicine.

Interactions: Before using Trichopol it is best to consult a doctor and apprise him of the treatment or medication (the term medication includes drugs bought without prescription and herbal medication) you are currently under and also get a prescription from your doctor before starting any new drug. This is to make sure that the combination of the two drugs is safe. Trichopol (Metranidazole) may react with the following:

• Anticoagulants such as Warfarin
• Ranolazine
• Typhoid vaccine taken orally
• Maraviroc
• Lithium preparations
• Eplerenone
• Disulfiram
• Drugs used to treat seizures
• Amprenavir oral solution
• Alcoholic beverages

Additional Information: Medicines should not be used without prior approval of a trained physician and don't share them with anybody else. Trichopol is made for specific conditions and it's not advisable to use it for other purposes. Keep medicinal drugs out of the reach of children.