Drug name: Duloxetine
Active Ingredients:
- duloxetine
Other names used:
- Ariclaim®
- Cymbalta®
- Xeristar®
- Yentreve®
Therapeutic effect of Duloxetine:
Duloxetine is a SNRI (serotonin-norepinephrine reuptake inhibitor) used for treating depression and anxiety disorders. This drug is also approved by Food and Drug Administration for the treatment of pain, especially musculoskeletal. Duloxetine is also very effective in reducing pain associated with diabetic peripheral neuropathy.
Indications: Duloxetine is used in the treatment of:
- Depression
- Pain associated with diabetic peripheral neuropathy (which is the damage to nerves due to high blood sugar)
Precautions and Restrictions: It is not advisable to take Duloxetine if you have one of the following conditions:
- High sensitivity to Duloxetine or similar substances
- Uncompensated - angle closure glaucoma
- If the user is a breast feeding mother
- Kidney or liver disorder, dilation of pupil (mydriasis), suicidal tendency, increase of irritable mood, pregnancy, seizures
Side effects of Duloxetine: Users of this drug may experience certain side effects that are associated with the use of Duloxetine. These side effects do not occur in all people who use this drug. Some of the adverse reactions that users of this drug may experience are:
- Dizziness but not vertigo
- Constipation, nausea, dry mouth
- Sleeplessness (Insomnia), headache (cephalalgia)
Some of the rare side effects are:
- Loss of weight, loss of appetite, tremors, vomiting, diarrhea
- Lack of sharpness of vision, flushing, Perspiration, weakness
- Inability to develop or maintain an erection of the penis during sexual performance
- Abnormal ejaculation, anorgasmia, low sex drive
The above mentioned side effects do not represent a comprehensive list of all the unintended reactions that the user of Duloxetine may experience. For the complete account of all side effects kindly consult a medical care provider, a pharmacist, or go through the report given by the maker of Duloxetine.
Interactions: If you are contemplating whether to start using Duloxetine, please consult a doctor and apprise him of the treatment or medication you are currently taking and also get a prescription from your doctor before starting any new drug in order to make sure that the combination of the two drugs is safe.
Duloxetine may react with the following substances:
- Medicines that has high affinity to blood proteins
- Monoamine oxidase inhibitors (MAOI)
- Central nervous system depressants
- Inhibitors of CYP2D6
- Drugs to alleviate mood disorders (antidepressants)
- Inhibitors of CYP1A2 such as some antibiotics
Additional Information: Medicines should not be used without prior approval of a qualified medical care provider and don't share these drugs with anybody else. Duloxetine tablets are made for specific conditions and it's not advisable to use them for other purposes. Keep medicinal drugs out of the reach of children.
